Non-allergic Asthma

In non-allergic asthma, disease onset and exacerbations result from factors unrelated to atopy. An episode may be caused by a range of triggers that include1,2:

  • Respiratory infection

  • Chronic rhinitis

  • Airborne irritants

  • Tobacco smoke

  • Exercise

  • Emotional stress

  • Gastroesophageal reflux

  • Non-atopic occupational exposures

  • Cold air

As with allergic asthma, management of non-allergic asthma requires accurate trigger identification and avoidance in addition to medications to control symptoms (as needed, based on disease severity).1,2

Asthma facts and figures

  • In the U.S., more than 20 million people have asthma3

  • Approximately 40% of asthma sufferers have non-allergic asthma4,5

  • 9 million U.S. children less than 18 years old have been diagnosed with asthma3

  • Asthma accounts for an estimated annual healthcare cost of $16.1 billion6

According to statistics from the U.S. Centers for Disease Control and Prevention, in 2002 there were3:

  • 14 million asthma-related outpatient visits to private physician offices and hospital clinics (of which 5 million involved children less than 18 years old)

  • 1.9 million asthma-related visits to emergency departments

  • 11.8 million work days missed due to asthma

  • 14.7 million school days missed due to asthma

Allergic vs. non-allergic: a key to asthma management

Effective management of asthma requires accurate identification and management of symptom triggers, as well as medications to control symptoms.1,2 Because such a large  proportion of asthma patients has allergic disease,4,5 accurate trigger identification necessitates the determination of the patient’s atopic status. To help aid your efforts, the Managing Asthma section of this Web site offers useful information, including guidelines from the National Asthma Education and Prevention Program (published by the National Institutes of Health, National Heart, Lung, and Blood Institute).