Disease Progression—the Allergy March

Asthma

Asthma can be either allergic or non-allergic. In children, allergic asthma can signify the culmination of the Allergy March, and evidence shows that asthma could have been mitigated or perhaps avoided through targeted treatment of allergic disease.1,2 The Early Treatment of the Atopic Child (ETAC) Study Group observed that some children with atopic dermatitis and other sensitivities being managed with cetirizine and allergen avoidance were half as likely to develop asthma as those left untreated.2 In addition, the Canadian Childhood Asthma Primary Prevention Study3 demonstrated a 56% reduction of asthma frequency by age 7 in high-risk children through an intervention program for the first year of their life that included avoidance of pets, secondhand smoke, and dust mites, and encouragement of breast-feeding.

Asthma facts and figures
Asthma is very common among children, and often appears with allergy.

  • More than 20 million people have asthma4

  • 60% of those with asthma suffer specifically from allergic asthma5

  • 9 million US children less than 18 years of age have been diagnosed with asthma4

  • 90% of children with asthma also have established allergies6

  • Approximately 40% of infants who have atopic dermatitis may develop asthma by the age of 3 to 4 years2

Why you should know the true cause of asthma triggers
Wheezing is a common precursor to asthma. Data have shown that one third of infant wheezers will develop asthma.7 In young patients, wheezing can have a number of possible causes including infection, congenital anomalies, and allergy. Among these, the latter is perhaps the most important risk factor not only for wheezing, but also for diminished lung function and, ultimately, asthma.8 To help clinicians determine which wheezers might develop asthma, the authors of the landmark Tucson Children’s Respiratory Study devised the Asthma Predictive
Index.9 According to the index, asthma is more probable in children who have had recurrent episodes of wheezing during the previous year, along with risk factors including atopic dermatitis or allergic rhinitis.

Click here to obtain expert asthma management guidelines from the National Institutes of Health.