Gain Knowledge in the Treatment of Common Childhood Illnesses With ImmunoCAP

 

Timely testing recommended
The challenge of identifying and managing allergy affects not only a child’s acute symptoms but also his or her long-term health. Early recognition of underlying atopic inflammation can help the clinician guide management in order to alter the course of disease progression. Research indicates that early intervention (through such measures as avoidance, antihistamine treatment, and immunotherapy) can help to reduce acute allergy symptoms and may interrupt the development of asthma.1-3 That’s why experts in pediatric allergy and diagnostic testing recommend timely allergy testing to confirm or rule out atopy and to identify specific allergens in order to help guide effective management.4-7 The European Academy of Allergy and Clinical Immunology (EAACI) Section on Pediatrics recommends testing:

  • for all children with allergy-like symptoms deemed to be severe, persistent, recurrent, or for those in need of continuous treatment for a particular illness, regardless of age4

Specific IgE assays make testing easy
ImmunoCAP Specific IgE blood testing makes it easy for primary care clinicians to perform an allergy evaluation.8 By utilizing pre-selected pediatric profiles of both food and airborne allergens, ImmunoCAP test results provide the pediatric clinician with clear evidence to rule in or rule out the presence of atopy, identify and quantify any specific allergic sensitivities, and guide effective management (including avoidance counseling, medication selection, and timely referral).

When used with the patient history and physical exam, ImmunoCAP provides objective quantifiable evidence of IgE-mediated allergen sensitivity to help the physician diagnose and manage these common childhood illnesses:

  • atopic dermatitis—the low-level allergic food sensitivities that cause dermatologic symptoms are often reflective of an ongoing disease process.9  When low-level sensitization is detected, the clinician may wish to  reassess at a later time to see if the sensitization is changing or becoming more significant.10 Identification of offending allergens can aid in guiding targeted avoidance (including elimination diets),11,12 which should be re-evaluated every 4-6 months.11 Due to a significant risk of malnourishment, great care should be taken when eliminating foods from a child's diet. Specialist consultation or referral is recommended.11

  • gastrointestinal distress—identification of food allergens can aid in guiding simple avoidance, more targeted elimination diets, or food challenges (specialist referral recommended)11,13,14

  • recurrent otitis media—when allergic rhinitis may be involved, experts recommend allergy testing to confirm atopy and treatment of this comorbid illness in order to aid control of otitis media11,15

  • allergic rhinitis—confirmation of atopy and identification of specific triggers will aid avoidance (to bring allergic load below the symptom threshold),10,16 and help guide treatment selection.8 Allergic rhinitis often accompanies recurrent otitis media and asthma, and experts recommend treatment of this disorder to aid the treatment11,15,17,18

  • asthma—management guidelines from both the NIH17 and the AAFP18 urge identification of allergens and other irritants to reduce exposure to these triggers

ImmunoCAP blood testing can be conducted on patients of any age, as young as 3 months, regardless of the medications they are already taking, and only a single blood draw is required. Many laboratories and reference laboratories offer ImmunoCAP Specific IgE blood testing.