Managing Childhood Diseases

Treatment Options for Recurrent Acute Otitis Media (OM)

Direct treatment of infection
Acute OM traditionally has been treated with antibiotics, either to target a confirmed bacterial infection or to help avoid one later. According to guidelines recently published by the American Academy of Pediatrics and the American Academy of Family Physicians, clinicians treating uncomplicated acute otitis media are now encouraged to consider the option of managing the pain and fever first, using only acetominophen or ibuprofen and waiting 48 to 72 hours to see if the infection begins to clear on its own.1 If the infection persists, then the first-line antibiotic for the treatment of acute OM should be amoxicillin. If the patient fails to respond within 48-72 hours, a second-line antibiotic should be used.1

The AAP/AAFP guidelines recommend the following options for second-line antibiotic therapy1:

  • Amoxicillin/clavulanate
  • Cefdinir
  • Ceftriaxone
  • Cefuroxime
  • Azithromycin
  • Clarithromycin

The role of underlying allergic inflammation
Allergy often plays a role in otitis media onset, especially when it recurs or is chronic. The condition is often caused by allergy-related eustachian tube dysfunction, whereby allergy causes inflammation of the tissues lining the eustachian tube. This inflammation hampers fluid drainage, thus trapping bacteria, which leads to infection.2 In fact, as many as 50% of children older than 3 years with chronic otitis media have confirmed allergic rhinitis.3 Once an atopic component is confirmed and allergic rhinitis is diagnosed, the clinician can treat the associated allergic rhinitis using a range of options:

  • Allergen avoidance
  • Antihistamine therapy
  • Intranasal corticosteroids
  • Intranasal cromolyn sodium

Click here for details on management options for concomitant allergic rhinitis. These steps will greatly aid the management of recurrent OM. According to the American Academy of Allergy, Asthma & Immunology, “When otitis media is associated with allergic rhinitis, control of allergic rhinitis frequently results in the resolution of otitis media.”2